Skip to main content
Anatolian Journal of Cardiology logoLink to Anatolian Journal of Cardiology
. 2014 Dec 25;15(1):79.

Author`s Reply

Oğuz Akkuş 1,
PMCID: PMC5336911  PMID: 25789378

To the Editor,

We thank all of the authors for their valuable comments, and we were delighted to see your interest to our study (1), entitled “Association of P-wave dispersion and left ventricular diastolic dysfunction in non-dipper and dipper hypertensive patients,” published in the April issue of The Anatolian Journal of Cardiology 2014; 14: 251-5.

  • 1)

    You are right about the mentioned parameters, such as e’, a’, and E/e’; this may be a deficiency of our study. Nevertheless, we will take your advice into consideration for future research.

  • 2)

    Deficient of normal fall of blood pressure at night is associated with increased risk of cardiovascular disease (2). Reverse-dipper or riser patients generate a small portion of hypertensive patients (3). Although this group is at risk for stroke (commonly intracranial hemorrhage), especially in elderly patients (4). However, despite the evidences, reverse-dipping is not mentioned in the valid guide- lines currently (5). The small number of patients was another deficiency in our study to obtain wide-angle data. Consequently, we did not examine and create a reverse-dipper group. Studies involving more patients with longer follow-ups may contribute valuable parts of further guidelines.

References

  • 1.Tosu AR, Demir S, Kaya Y, Selçuk M, Akdağ S, Işık T, et al. Association of P wave dispersion and left ventricular diastolic dysfunction in non-dipper and dipper hypertensive patients. Anadolu Kardiyol Derg. 2014;14:251–5. doi: 10.5152/akd.2014.4668. [CrossRef] [DOI] [PubMed] [Google Scholar]
  • 2.Ohkubo T, Imai Y, Tsuji I, Nagai K, Watanabe N, Minami N, et al. Relation between nocturnal decline in blood pressure and mortality. The Ohasama Study. Am J Hypertens. 1997;10:1201–7. doi: 10.1016/s0895-7061(97)00274-4. [CrossRef] [DOI] [PubMed] [Google Scholar]
  • 3.Salwa P, Gorczyca-Michta I, Kluk M, Dziubek K, Wozakowska-Kaplon B. Variability of circadian blood pressure profile during 24-hour ambulatory blood pressure monitoring in hypertensive patients. Kardiol Pol. 2014;5:432–7. doi: 10.5603/KP.a2014.0018. [CrossRef] [DOI] [PubMed] [Google Scholar]
  • 4.Kario K, Pickering TG, Matsuo T, Hoshide S, Schwartz JE, Shimada K. Stroke prognosis and abnormal nocturnal blood pressure falls in older hyperten-sives. Hypertension. 2001;4:852–7. doi: 10.1161/hy1001.092640. [CrossRef] [DOI] [PubMed] [Google Scholar]
  • 5.Taylor J. 2013 ESH/ESC guidelines for the management of arterial hyperten-sion. Eur Heart J. 2013;28:2108–9. [PubMed] [Google Scholar]

Articles from Anatolian Journal of Cardiology are provided here courtesy of Turkish Society of Cardiology

RESOURCES