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Anatolian Journal of Cardiology logoLink to Anatolian Journal of Cardiology
letter
. 2015 Jan 21;15(2):161. doi: 10.5152/akd.2015.5878

Fragmented QRS and myocardial performance index in nephrotic syndrome

Sim Sai Tin 1,, Viroj Wiwanitkit 1
PMCID: PMC5337005  PMID: 25625446

To the Editor,

The recent report on “Fragmented QRS and myocardial performance index in nephrotic syndrome” published is very interesting (1). Özkan et al. (1) concluded that the “determination of fQRS in patients with nephrotic syndrome (NS) in surface ECG, an easily accessible technique, can be used as a parameter in the prediction of myocardial functions.” In fact, it is already known that “fQRS may be useful in identifying patients at higher cardiac risk with larger areas of ischemic jeopardized or necrotic myocardium (2).” Hence, the similar finding among patients with NS is not a surprising finding. Nevertheless, an important factor to be concerned in the patient with NS is the medication. In the case of long-term use of steroid, the effect on the QRS can be expected (3), and this might decrease the utility of fragmented QRS detection. In the present report (1), the use of steroid is not mentioned well, and its effect on the diagnostic property of fragmented QRS is an interesting issue to be discussed.

References

  • 1.Özkan G, Adar A, Ulusoy S, Bektaş H, Kırış A, Fidan M, et al. Presence of fragmented QRS and its correlation with myocardial performance index in patients with nephrotic syndrome. Anatolian J Cardiol. 2014;14:450–5. doi: 10.5152/akd.2014.4886. [CrossRef] [DOI] [PubMed] [Google Scholar]
  • 2.Kocaman SA, Çetin M, Kırış T, Erdoğan T, Çanga A, Durakoğlugil E, et al. The importance of fragmented QRS complexes in prediction of myocardial infarction and reperfusion parameters in patients undergoing primary percutaneous coronary intervention. Turk Kardiyol Dern Ars. 2012;40:213–22. doi: 10.5543/tkda.2012.36937. [CrossRef] [DOI] [PubMed] [Google Scholar]
  • 3.Ito T, Su KM, Murata M, Koizumi T, Matsumoto S, Ito Y, et al. Experimental studies on the effect of glucocorticoids on cardiac muscle. Recent Adv Stud Cardiac Struct Metab. 1976;12:203–10. [PubMed] [Google Scholar]

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