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. 2016 Nov 4;31(3):645–653. doi: 10.1038/leu.2016.258

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DT204+BTZ triggers synergistic inhibition of MM xenograft growth in vivo. (a) Representative bioluminescence imaging of mice from each treatment group at day 18 after treatment initiation. (b) Animal body weight after treatment with vehicle, DT204, BTZ or DT204+BTZ combination. (c) Kaplan–Meier survival curve comparison of nude mice after subcutaneous injection of myeloma cells treated with vehicle, DT204, BTZ or DT204+BTZ. (d) Western blot of p27 from tumor tissue of mice treated with vehicle, BTZ, DT204 or both.