Table 3. Univariate and multivariate analyses of disease-free survival in ovarian cancer patients.
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
Variables | Hazard ratio [95%CI] | p value | Hazard ratio [95%CI] | p value |
Age (> 50) | 1.62 [1.05–2.48] | 0.028 | 1.46 [0.92–2.30] | 0.108 |
FIGO stage (III/IV) | 6.30 [2.90–13.68] | < 0.001 | 4.61 [2.10–10.13] | < 0.001 |
Cell type (non-serous) | 0.37 [0.22–0.64] | < 0.001 | 0.63 [0.36–1.12] | 0.119 |
Grade (poor) | 1.86 [1.20–2.88] | 0.006 | 1.73 [1.09–2.73] | 0.019 |
CA125 (> 35 U/ml) | 1.96 [0.94–4.05] | 0.071 | NA | |
FILIP1L- | 2.42 [1.49–3.93] | < 0.001 | 2.03 [1.21–3.41] | 0.008 |
Beta-catenin+ | 1.32 [0.87–2.00] | 0.192 | NA | |
SLUG+ | 1.55 [1.01–2.38] | 0.044 | 1.89 [1.20–2.95] | 0.006 |
FILIP1L-/Beta-catenin+ | 3.88 [1.78–8.46] | 0.001 | 3.42 [1.53–7.64] | 0.003 |
FILIP1L-/SLUG+ | 2.41 [1.34–4.34] | 0.003 | 2.52 [1.36–4.65] | 0.003 |
Beta-catenin+/SLUG+ | 1.97 [1.09–3.56] | 0.024 | 2.76 [1.44–5.32] | 0.002 |
Abbreviations: FIGO, International Federation of Gynecology and Obstetrics; CI, confidence interval; NA, not applicable.