Particle adhesion to inflamed mesentery endothelium as a function of modulus and size. (A) Schematic of mouse surgical technique for intravital imaging, as described in the methods. (B) Representative fluorescence images of particle adhesion to inflamed mesentery, images correspond particles A-2μm and D-2μm (top to bottom). Particle fluorescence shown in red, overlaid on the bright field image. Scale bar is 50 μm. (C) Quantified adhesion efficiency of hydrogel particle conditions A-2μm, D-2μm, A-500nm, and D-500nm, scaled by vessel area, n = 4 mice per group. Statistical analysis was performed using one-way ANOVA with Fisher’s LSD test within particle sizes. (**) indicates p<0.01 and (****) indicates p<0.0001. Error bars represent standard error.