Skip to main content
. 2016 Sep 16;7(45):73769–73780. doi: 10.18632/oncotarget.12063

Figure 4. Transcriptional consequences of lncRNA modulation in the context of ETV6/RUNX1 rearranged leukemia cases.

Figure 4

A. RT-qPCR analysis of lncRNA knockdown experiments using two independent LNA GapmeRs for each lncRNA. This plot is representative for three independent biological replicates and knockdown was evaluated with three different primer pairs for each lncRNA. B. MA-plots, which display the mean expression and fold change of RNA sequencing data of REH cells upon lnc-NKX2-3-1 and lnc-RTN4R-1 knockdown. Significantly differentially expressed genes are represented in red. C. Functional annotation of genes down- and up-regulated upon lnc-RTN4R-1 knockdown in REH cell line.