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. 2016 Sep 16;7(45):73817–73829. doi: 10.18632/oncotarget.12074

Figure 2. SHP2 promotes melanoma cell viability, motility, and anchorage-independent growth.

Figure 2

A. SHP2 overexpression enhances MeWo cell viability, and SHP2 knockdown reduces MeWo cell viability. B. SHP2 overexpression in MeWo cell enhances proliferation and supresses apoptosis, and SHP2 knockdown supresses proliferation and enhance apoptosis. C. SHP2 overexpression in MeWo cell increases Ki67-positive (i.e. proliferative) cells, and SHP2 knockdown decreases Ki67-positive cells. SHP2 overexpression promotes MeWo cell D. movement E. moving speed F. migration and H. anchorage-independent growth. G. SHP2 knockdown slows down the MeWo cell migration.