Table 3. Predictive value of biomarkers for progression-free survival (univariate analysis with continuous values).

	HR	95%-CI	p
Value at D1
VEGF-C (ng/ml) J0	0.93	(0.70-1.26)	0.66
sE-SELECTIN (ng/ml) J0	0.99	(0.94-1.04)	0.62
THROMBOSPONDIN (μg/ml) J0	0.99	(0.96-1.04)	0.96
VEGF (ng/ml) J0	1.96	(0.98-3.92)	0.06
PIGF (pg/ml) J0	0.98	(0.91-1.06)	0.68
SCF sR/c-kit (ng/ml) J0	0.99	(0.66-1.49)	0.98
Value at D7
VEGF-C (ng/ml) J7	0.91	(0.63-1.31)	0.61
sE-SELECTIN (ng/ml) J7	1.01	(0.96-1.06)	0.70
THROMBOSPONDIN (μg/ml) J7	0.98	(0.93-1.03)	0.39
VEGF (ng/ml) J7	2.15	(0.92-5.06)	0.08
PIGF (pg/ml) J7	1.01	(0.96-1.05)	0.84
SCF sR/c-kit (ng/ml) J7	1.04	(0.74-1.45)	0.83
Difference (D7-D1)
VEGF-C (ng/ml) J7 - J0	0.89	(0.45-1.77)	0.73
sE-SELECTIN (ng/ml) J7 - J0	1.07	(0.99-1.16)	0.08
THROMBOSPONDIN (μg/ml) J7 - J0	0.98	(0.93-1.03)	0.36
VEGF (ng/ml) J7 - J0	0.40	(0.04-3.91)	0.43
PIGF (pg/ml) J7 - J0	1.01	(0.97-1.06)	0.66
SCF sR/c-kit (ng/ml) J7 - J0	1.45	(0.53-3.95)	0.47