Table 5. Credibility of the Association for CD44 Variants and Cancer Risk.
| Genetic variant | *Overall scheme | Cumulative evidence |
|---|---|---|
| CD44 rs13347 | ABB | Moderate |
| CD44 rs11821102 | CCA | Weak |
| CD44 rs10836347 | CCA | Weak |
| CD44 rs713330 | CCA | Weak |
| CD44 rs187115 | BBB | Moderate |
*
First letter refers to the Amount of evidence that was assessed by counting the number of minor alleles. Grade A, B and C correspond if nminor =>1,000, 100-1000 and <100, respectively where nminor the total number of cases and controls with the least frequent genotype. Second letter refers replication assessment and the third letter demonstrated protection from bias [50].