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. 2016 Sep 24;7(44):71504–71513. doi: 10.18632/oncotarget.12229

Figure 2. Tumor-related miRNA regulatory pathways.

Figure 2

(A) The distribution of differentially expressed miRNAs in different number of tumor types. (B) Network of miR-92a-3p, miR-142-5p, miR-193b-3p and miR-423-3p regulating five of the six pathways. (C) miRNA target network in TGF-β signaling pathway regulated by those four miRNAs. (D) The expression profiles of miR-142-5p normalized by log2 in nine tumor types. T test, *P < 0.05, **P < 0.01, ***P < 0.001. (CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, BRCA: Breast invasive carcinoma, ESCA: Esophageal carcinoma, KIRC: Kidney renal clear cell carcinoma, UCEC: Uterine Corpus Endometrial Carcinoma, PAAD: Pancreatic adenocarcinoma, SKCM: Skin Cutaneous Melanoma, LIHC: Liver hepatocellular carcinoma, THCA: Thyroid carcinoma).