. 2016 Sep 28;7(44):71727–71736. doi: 10.18632/oncotarget.12327

Table 2. Correlations of NEmarkers and NE features with clinicopathlogical parameters.

Factors		CD56		P	CgA		P	Syn		P	NE		P	P53		P
		−	+		−	+		−	+		−	+		−	+
		n	n		n	n		n	n		n	n		n	n
Sex	Male	294	46	0.805	247	93	0.055	278	62	0.43	279	61	0.389	107	223	0.601
Sex	Female	97	14	0.805	70	41	0.055	87	24	0.43	87	24	0.389	32	79	0.601
Age	< 65	273	40	0.622	221	96	0.823	250	63	0.389	258	55	0.297	99	214	0.575
Age	≥ 65	118	20	0.622	92	42	0.823	115	23	0.389	108	30	0.297	40	98	0.575
Family History	No	312	48	0.97	254	106	0.71	292	68	0.774	294	66	0.516	249	111	0.928
Family History	Yes	77	12	0.97	61	28	0.71	71	18	0.774	70	19	0.516	62	27	0.928
Smoking	Never	128	16	0.348	92	52	0.042	114	30	0.514	115	29	0.631	41	103	0.46
Smoking	Ever/Current	263	44	0.348	225	82	0.042	251	56	0.514	251	56	0.631	98	209	0.46
Alcohol	Never	199	28	0.505	157	70	0.452	184	43	0.818	188	39	0.533	66	161	0.365
Alcohol	Ever/Current	189	32	0.505	160	61	0.452	181	40	0.818	178	43	0.533	73	148	0.365
Histologic type	Squamous cell carcinoma	209	17	< 0.001	188	38	< 0.001	197	29	0.001	204	22	< 0.001	80	146	0.027
	Adenocarcinoma	174	41		123	92		159	56		154	61		54	161
	Others^*	8	2		6	4		9	1		8	2		5	5
Grade	High-middle	202	20	0.008	182	42	< 0.001	189	33	0.017	194	28	0.001	70	152	0.658
Grade	Middle-low-low	184	39	0.008	132	91	< 0.001	170	53	0.017	167	56	0.001	66	157	0.658
Clinical stage	I	168	15	< 0.001	139	44	0.082	153	30	0.017	163	20	< 0.001	57	126	0.854
	II	97	14		77	34		87	24		88	23		36	75
	III	126	31		102	55		125	32		115	42		46	111

Otherhistologic type includes alveolar cancer, neuroendocrine cancer, giant cell carcinoma, carcinosarcoma, pleomorphic carcinoma and pulmonary blastoma and others.