Figure 2. Effects of plasma exosomes derived from SF(−) or SF(+) mice on mouse lung TC1 cell on proliferation, migration, and invasion.

Compared to corresponding SC conditions, SF induces accelerated tumor cell proliferation and migration in TC1 tumor cells (n = 12) as shown in Panel (A) – proliferation assay, and Panel (B) – migration assay. The invasion of TC1 cells assessed by 3D culture panel (C) showed a trend towards increases invasion exerted by exosomes from SF(+) mice (n = 7).