Table 1. RCT studies selecting conversion resection after conversion therapy.
Study | Num | Regimens | ORR | R0 R | Jadad |
---|---|---|---|---|---|
RAISE[15] | 536 | FOLFIRI+Ramu | 13.4 | ---- | 6 |
536 | FOLFIRI | 12.5 | |||
Ranhua 2015 [16] | 65 | FOLFIRI+Beva | 47.7 | ---- | 7 |
77 | FOLFIRI | 28.6 | 7 | ||
Marc 2010 [17] | 303 | FOLFIRI+Pani | 40.0 | ---- | 5 |
294 | FOLFIRI | 9.9 | |||
Eric 2012 [18] | 611 | FOLFIRI+Afli | 19.8 | ---- | 5 |
605 | FOLFIRI | 11.1 | |||
Le-Chi 2013 [19] | 70 | mFOLFOX6+Cetu | 57.1 | 25.7 | 4 |
68 | mFOLFOX6 | 29.4 | 7.4 | ||
Eric 2009 [20] | 599 | FOLFIRI+Cetu | 46.9 | 5.1 | 7 |
599 | FOLFIRI | 38.7 | 2.0 | ||
Yuguo 2015 [21] | 65 | FOLFIRI+Pani+beva | 46.2 | ---- | 5 |
77 | FOLFIRI | 26.0 | |||
Carsten 2009 [22] | 113 | FOLFOX4+Cetu | 32.7 | 16.0 | 6 |
120 | FOLFOX4 | 22.5 | 4.3 | ||
MAC CION [23] | 362 | CAP/FOLFOX/+Cetu | 40.9 | 15.0 | 5 |
367 | CAP/FOLFOX | 32.4 | 13.0 | ||
PRIME [24] | 326 | FOLFOX4+Pani | 54.9 | 8.3 | 6 |
331 | FOLFOX4 | 48.0 | 7.0 | ||
FIRE-3 [25] | 297 | FOLFIRI+Cetu | 62.0 | ---- | 7 |
295 | FOLFIRI+Beva | 58.0 | |||
PEAK [26] | 139 | mFOLFOX6+Pani | 59.0 | ---- | 7 |
139 | mFOLFOX6+Beva | 54.7 | |||
CALGB/SWOG 80405 [27] | 270 | FOLFIRI/OX+Cetu | 68.9 | 5 | |
256 | FOLFIRI/OX+Beva | 55.9 |