Figure 6. NPM1 and its two Thr199 and Thr234/237 phosphorylated forms were overexpressed in human CRPC.

68 human PCa slides were immunostained using NPM1, Thr199 NPM1 and Thr234/237 NPM1 primary antibodies. A. Pictures representing the different expressions in castration resistant prostate cancer (CRPC), in androgen-dependent prostate cancer (ADPC) and in normal peri-tumoral zones. Scale bar, 250 μm. B. Staining quantifications in CRPC and ADPC using quick scores defined by the intensity and the percentage of stained cells. The p values were obtained using ANOVA unpaired t-test.