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. 2016 Sep 12;7(43):69770–69782. doi: 10.18632/oncotarget.11974

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Copyright: © 2016 Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Left panel: The wound healing assay was conducted to detect the cell migration in glioma cells after Cdc20 shRNA and rottlerin treatment. Control: siRNA control; Rottlerin: 2 μM rottlerin; shRNA: Cdc20 shRNA; Both: rottlerin + Cdc20 shRNA. Right panel: Quantitative results are illustrated for left panel. *P < 0.05, vs control; ^#P < 0.05 vs Cdc20 shRNA treatment or rottlerin treatment. (B) Left panel: The expression of Cdc20 and its target p21 was detected by western blotting in glioma cells with Cdc20 shRNA and rottlerin treatment. Right panel: Quantitative results are illustrated for left panel. *P < 0.05, **P < 0.01, compared with control; ^#P < 0.05 compared with rottlerin treatment or Cdc20 shRNA treatment.