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. 2016 Sep 30;7(46):75712–75728. doi: 10.18632/oncotarget.12362

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Copyright: © 2016 Costa et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. Heatmap of the microarray analyses showed 742 transcripts upregulated and 598 transcripts downregulated in Rb^f/f; K14creER^TM;E2F4^−/− compared to Rb^f/f;K14creER^TM;E2F1^−/. B, C. Enrichment analyses of Gene Ontology of the downregulated (B) and upregulated (C) genes. D, E. ChEA analyses showing the transcription factors exclusively regulating the downregulated (D) and upregulated genes (E). F. ChEA analyses showing the transcription factors involved in the regulation of both upregulated and downregulated.