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. 2016 Oct 3;7(46):75790–75799. doi: 10.18632/oncotarget.12414

Figure 6. Effects of lumbar puncture-administered resveratrol on STAT3 signaling and autophagy-related protein expression.

Figure 6

A. p-STAT3 immunohistochemical staining and immunofluorescence (IF) co-labeling of LC3 (green) and Beclin1 (red) were performed on rat intracranial glioblastomas treated by lumbar puncture with 0.3% DMSO (Control) or trans-resveratrol (Res); the insets are the enlarged images (×40). B. Western blot analysis of LC3, Beclin1, STAT3 and p-STAT3 expression in normal brain (Brain) and RG2-derived orthotopic tumors treated by lumbar puncture with 0.3% DMSO (Control) or resveratrol (Res). β-actin was used as quantitative control for calculating LC3, Beclin1, STAT3 and p-STAT3 levels in densitometry analyses.