Genome Research 13: 875-882 (2003)
Genomic gene clustering analysis of pathways in eukaryotes
Jennifer M. Lee and Erik L.L. Sonnhammer
The authors have discovered an error in part of the analysis of pathways in S. cerevisiae described in Table 1 and wish to correct the data. The corrected table is reprinted below. The authors apologize for any inconvenience this error may have caused other investigators in the field.
Table 1.
Pathways Analyzed and Percentage Showing Significant Clustering in Unmerged and Merged Data Sets
| Organism | # Pathways analyzed | # Genes | % Significant unmerged data | % Significant merged data | % in random data |
|---|---|---|---|---|---|
| H. sapiens | 98 | 975 | 78% | 65% | 11% |
| C. elegans | 86 | 516 | 74% | 58% | 11% |
| D. melanogaster | 85 | 484 | 50% | 30% | 12% |
| A. thaliana | 79 | 318 | 60% | 43% | 11% |
| S. cerevisiae | 89 | 682 | 35% | 20% | 10% |
The percent significant refers to pathways in which the score is more than 3* (3rd quartile – median) + median. The same analysis was carried out on randomized pathways where genes were picked randomly from all genes, using the merged data