Table 2. Quality assessment.

Included studies	Year	Method of randomization	Allocation concealment	Blind	Withdrawal and dropout	Baseline	Quality levela
Burger [9]	2011	centralized	central office	yes	Detailed criteria	identical baseline	A
Perren [10]	2011	centralized	central office	no	Detailed criteria	identical baseline	A
Pujade-Lauraine [15]	2014	No detailed	No detailed	no	Detailed criteria	identical baseline	B
Aghajanian [50]	2012	centralized	central office	yes	Detailed criteria	identical baseline	A
Gotlieb [51]	2012	centralized	central office	yes	Detailed criteria	identical baseline	A
Karlan [52]	2012	centralized	central office	yes	Detailed criteria	identical baseline	A
Monk [53]	2014	centralized	central office	yes	Detailed criteria	identical baseline	A
Pignata [54]	2015	centralized	central office	no	Detailed criteria	identical baseline	A
Vergote [55]	2013	centralized	central office	yes	Detailed criteria	identical baseline	A
Kaye [56]	2012	centralized	central office	no	Detailed criteria	identical baseline	A
Makhija [57]	2010	centralized	central office	yes	Detailed criteria	identical baseline	A
Kaye [58]	2013	No detailed	no detailed	no	Detailed criteria	identical baseline	B
Meier [59]	2012	centralized	central office	no	Detailed criteria	identical baseline	A
Naumann [60]	2013	centralized	central office	no	Detailed criteria	identical baseline	A
Cognetti [61]	2013	centralized	central office	yes	Detailed criteria	identical baseline	A
Raja [62]	2013	centralized	central office	yes	Detailed criteria	identical baseline	A
Oza [63]	2015	centralized	central office	no	Detailed criteria	identical baseline	A
Kummar [64]	2015	No detailed	no detailed	no	no detailed	identical baseline	C
Kurzeder [65]	2015	centralized	central office	yes	Detailed criteria	identical baseline	A
Liu [66]	2014	No detailed	no detailed	no	Detailed criteria	identical baseline	B
Lorusso [67]	2014	No detailed	no detailed	no	Detailed criteria	identical baseline	B
Birrer [68]	2013	centralized	central office	yes	Detailed criteria	identical baseline	A
Pujade-Lauraine [69]	2013	No detailed	no detailed	no	Detailed criteria	identical baseline	B
Hainsworth [70]	2015	No detailed	no detailed	no	Detailed criteria	identical baseline	B
Konecny [71]	2014	centralized	central office	yes	Detailed criteria	identical baseline	A
Lhommè [72]	2008	No detailed	no detailed	no	Detailed criteria	identical baseline	B
McNeish [73]	2014	centralized	central office	no	Detailed criteria	identical baseline	A
Coleman [74]	2014	No detailed	no detailed	no	Detailed criteria	identical baseline	B
Du Bois [75]	2013	centralized	central office	yes	Detailed criteria	identical baseline	A
Oza [76]	2015	No detailed	no detailed	no	Detailed criteria	identical baseline	B

^aSee Methods for definition