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. 2016 Oct 14;7(50):82876–82888. doi: 10.18632/oncotarget.12657

Figure 2. LYN promotes lung ADC progression.

Figure 2

A. LYN protein levels were determined by western blot. B. siRNA-mediated LYN knockdown was confirmed by western blot in H358, H1792, and H1975 cells. NT, non-targeting. To verify the specificity of siRNA-mediated LYN knockdown, levels of SRC, a major member of the SFK family, was analyzed by western blot. The effects of LYN knockdown on cell proliferation (left), migration (center), and invasion (right) were evaluated using the WST-1 assay (proliferation) and the Boyden chamber assay (migration and invasion; n = 3; Bars, SE; *, P < 0.05; Student's t-test). C. LYN overexpression was confirmed by western blot in H1703, HCC2108, and SK-LU-1 cells. VEC, empty vector. Phenotypes assayed as above.