Table 2. The comparison of the genotypes and alleles of eight study polymorphisms between HCC patients and controls.
Polymorphisms | Class | WW | WM | MM | *P | M | P |
---|---|---|---|---|---|---|---|
rs199514452 | AA | AT | TT | T | |||
c.31T > A | Patients | 170 | 78 | 9 | 0.847 | 18.66% | 0.837 |
Controls | 175 | 82 | 7 | 18.18% | |||
rs201540428 | TT | TA | AA | A | |||
c.34A > T | Patients | 163 | 84 | 10 | 0.754 | 20.23% | 0.447 |
Controls | 159 | 93 | 12 | 22.16% | |||
rs201614260 | CC | CG | GG | G | |||
c.84G > C | Patients | 218 | 39 | 0 | 0.043 | 7.59% | 0.039 |
Controls | 240 | 24 | 0 | 4.55% | |||
rs17879702 | CC | CT | TT | T | |||
c.133C > T | Patients | 201 | 52 | 4 | 0.021 | 11.67% | 0.007 |
Controls | 230 | 32 | 2 | 6.82% | |||
rs17880292 | GG | GA | AA | A | |||
c.256G > A | Patients | 215 | 42 | 0 | 0.177 | 8.17% | 0.673 |
Controls | 221 | 39 | 4 | 8.90% | |||
rs17879599 | GG | GC | CC | C | |||
c.299G > C | Patients | 129 | 113 | 15 | < 0.001 | 27.82% | < 0.001 |
Controls | 177 | 76 | 11 | 18.56% | |||
rs17424145 | TT | TC | CC | C | |||
c.341T > C | Patients | 227 | 30 | 0 | 0.311 | 5.84% | 0.277 |
Controls | 241 | 23 | 0 | 4.36% | |||
rs35445101 | AA | AG | GG | G | |||
c.790T > C | Patients | 213 | 43 | 1 | 0.247 | 8.75% | 0.193 |
Controls | 210 | 49 | 5 | 11.17% |
Abbreviations: WW, homozygous wild genotype; WM, heterozygous genotype; MM, homozygous mutant genotype; M, mutant allele. P was calculated by the *Fisher's exact test for genotype comparisons and by the χ2-test for allele comparisons between patients and controls.