Table 4. Associations between variant TINCR genotypes and clinicopathologic characteristics of gastric cancer.
Variable | GA+AA, GG for rs8113645 | Allelic odds ratios and 95% confidence intervals for rs8113645 | AG+GG, AA for rs2288947 | Allelic odds ratios and 95% confidence intervals for rs2288947 | ||||
---|---|---|---|---|---|---|---|---|
CT+TT, n | CC, n | Adjusted OR(95%CI)* | P value | AG+GG, n | AA, n | Adjusted OR (95% CI)* | P value | |
Tumor differentiation | ||||||||
Moderate | 30 | 103 | 0.93 (0.29-2.92) | 0.896 | 64 | 69 | 0.90 (0.35-2.30) | 0.825 |
Poor | 95 | 351 | 1.01 (0.36-2.83) | 0.982 | 204 | 242 | 0.97 (0.41-2.29) | 0.943 |
Depth of tumor infiltration | ||||||||
T2 | 11 | 57 | 0.87(0.37-2.07) | 0.752 | 34 | 34 | 1.12(0.57-2.22) | 0.746 |
T3 | 69 | 200 | 1.43 (0.79-2.58) | 0.240 | 118 | 151 | 0.86 (0.53-1.40) | 0.547 |
T4 | 32 | 143 | 0.90 (0.46-1.76) | 0.750 | 84 | 91 | 1.03 (0.61-1.75) | 0.905 |
Lymph node metastasis | ||||||||
Positive | 84 | 322 | 0.85 (0.56-1.28) | 0.431 | 184 | 222 | 0.87(0.62-1.23) | 0.428 |
Localization | ||||||||
Noncardia | 78 | 258 | 1.22(0.82-1.82) | 0.327 | 167 | 169 | 1.32 (0.95-1.84) | 0.094 |
* Adjusted for age, sex, smoking status, residence, hypertension, and diabetes.