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. 2016 Dec 30;8(4):5861–5873. doi: 10.18632/oncotarget.14390

Table 2. EGFR Exon 19 del and Exon 21 L858R Mutations Detected in Plasma cfDNA (ddPCR) Versus Paired Tumor Tissues (ARMS).

Plasma cfDNA Tumor tissues Total Sensitivity Specificity Consistency rate κ P
+
Exon19 del or
Exon 21L858R
+ 57 4 61 61.3% 96.7% 81.4% 0.605 <0.001
36 118 154
Total 93 122 215
Exon 19del
+ 26 2 28 57.8% 98.8% 90.2% 0.657 <0.001
19 168 187
Total 45 170 215
Exon 21L858R
+ 31 3 34 64.6% 98.2% 90.7% 0.701 <0.001
17 164 181
Total 48 167 215