Table 3. Stratified analysis between CD55 rs2564978 genotypes and NSCLC risk.
| Variables | Genotypes (Cases/Controls) | CC/TT model OR (95% CI)a | P value | ||
|---|---|---|---|---|---|
| Sex | |||||
| Male | 127/178 | 252/216 | 92/80 | 1.69 (1.14–2.49) | 0.008 |
| Female | 69/64 | 110/124 | 56/44 | 1.14 (0.67–1.92) | 0.624 |
| Age | |||||
| ≤ 60 | 108/132 | 197/183 | 85/75 | 1.37 (0.91–2.06) | 0.134 |
| > 60 | 88/110 | 165/157 | 63/49 | 1.75 (1.08–2.82) | 0.022 |
| Smoking status | |||||
| Non-smoker | 110/160 | 194/252 | 86/94 | 1.30 (0.88–1.90) | 0.184 |
| Smoker | 86/82 | 168/88 | 62/30 | 2.01 (1.18–3.43) | 0.010 |
| Pack-year of smoking | |||||
| ≤ 30 | 47/44 | 104/54 | 37/18 | 1.95 (0.96–3.94) | 0.063 |
| > 30 | 39/38 | 64/34 | 25/12 | 2.00 (0.87–4.57) | 0.102 |
| Histological types | |||||
| Adenocarcinomas | 110/242 | 210/340 | 84/124 | 1.35 (1.01–1.80) | 0.042 |
| Squamous cell | 81/242 | 134/340 | 58/124 | 0.06 (0.99–2.30) | 0.057 |
| Other carcinomasb | 5/242 | 18/340 | 6/124 | 2.36 (0.70–7.95) | 2.361 |
aData were calculated by unconditional logistic regression and adjusted for sex, age and smoking status.
bOther carcinomas: adenosquamous carcinoma (n = 15), large cell carcinoma (n = 5), alveolar carcinoma (n = 9).