Table 3. Patients' characteristics (n=437).
| Total n (%) | Normal/failing karyotype n(%) | Abnormal karyotype n(%) | |
|---|---|---|---|
| N. of patients | 437 (100.0) | 240 (54.9) | 197 (45.1) |
| Median age (years) (range) | 51 (16-84) |
51 (16-84) |
51 (16-82) |
| Sex | |||
| Male | 276 (63.2) | 146 (60.8) | 130 (66.3) |
| Median Hb (g/L) (range) |
76 (28-173) |
76 (28-173) |
76 (35-153) |
| Median ANC (×109/L) (range) | 1.16 (0-20.53) |
1.15 (0.09-20.53) |
1.16 (0-13.21) |
| Median platelet count (×109/L) (range) | 65 (2-1561) |
63 (5-1024) |
69 (2-1561) |
| WHO 2008 | |||
| RCUD | 12 (2.7) | 7 (2.9) | 5 (2.5) |
| RARS | 15 (3.4) | 10 (4.2) | 5 (2.5) |
| RCMD | 231 (52.9) | 135 (56.3) | 96 (48.7) |
| RAEB-1 | 86 (19.7) | 49 (20.4) | 37 (18.8) |
| RAEB-2 | 77 (17.6) | 36 (15.0) | 41 (20.8) |
| MDS-U | 11 (2.5) | 3 (1.3) | 8 (4.1) |
| 5q- syndrome | 5 (1.1) | 0 (0.0) | 5 (2.5) |
| IPSS risk category | |||
| Low | 39 (8.9) | 32 (13.3) | 7 (3.6) |
| Int-1 | 277 (63.4) | 182 (75.8) | 95 (48.2) |
| Int-2 | 95 (21.7) | 26 (10.8) | 69 (35.0) |
| High | 26 (5.9) | 0 (0.0) | 26 (13.2) |
| IPSS-R risk category | |||
| Very low | 15 (3.4) | 14 (5.8) | 1 (0.5) |
| Low | 116 (26.5) | 85 (35.4) | 31 (15.7) |
| Intermediate | 138 (31.6) | 84 (35.0) | 54 (27.4) |
| High Very high |
102 (23.3) 66 (15.1) |
50 (20.8) 7 (2.9) |
52 (26.4) 59 (29.9) |