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. 2016 Jul 18;8(5):7502–7520. doi: 10.18632/oncotarget.10649

Figure 2. The effects of BTG1 overexpression on differentiation and autophagy of colorectal cancer cells.

Figure 2

BTG1 transfectants showed better differentiation, evidenced by alkaline phosphatase activity A. and tight junction under transmission electron microscope (TEM, B, white arrow). There was a high autophagy evidenced by autophagosome under TEM (B., green arrow) and LC-3B expression C. in BTG1 transfectants, compared with the control. Higher expression of Beclin-1, Atg7 and Atg14 was observed in BTG1 transfectants than the mock and control D. *, p<0.05, compared with the transfectants.