Table 2. Comparisons of AUC for the discrimination between breast cancer and benign tissue by BPER.

	Menopause status	Phase	AUC	95%CI	P	Cutoffpoint	Sensitivity	Specificity
Cancer vs normal	Premenopausal	Early	0.665	0.555-0.775	0.006
		Mid	0.704	0.599-0.808	0.001	40.3%	65.96%	68.09%
		Late	0.687	0.580-0.794	0.002
	Postmenopausal	Early	0.668	0.567-0.769	0.003	10.05%	87.04%	40.74%
		Mid	0.647	0.543-0.751	0.008
		Late	0.631	0.524-0.738	0.019
Cancer vs benign	Premenopausal	Early	0.554	0.437-0.672	0.364
		Mid	0.622	0.509-0.736	0.041	51.4%	46.81%	78.72%
		Late	0.581	0.465-0.698	0.173
	Postmenopausal	Early	0.633	0.529-0.738	0.017	13.3%	72.22%	46.3%
		Mid	0.565	0.456-0.674	0.244
		Late	0.545	0.436-0.654	0.421

AUC, area under the curve; BPER, background parenchymal enhancement rate; CI, confidence interval