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. 2016 Nov 25;8(3):5603–5618. doi: 10.18632/oncotarget.13629

Figure 2. VEGF-C enhances the cancer stemness properties in skin cancer.

Figure 2

a-g. QRT-PCR analysis of the SOX2, OCT4, KLF4, NANOG, CD133, CD34 and CD44 mRNA expression in indicated cells with rhVEGF-C (200 ng/ml) treatment. h. ALDH activity of the indicated cells was measured by flow cytometry. i-q. Expression of VEGF-C (i) and Slug (j) was detected, and Slug expression restores the expression of CSC markers (SOX2 (k), OCT4 (l), KLF4 (m), NANOG (n), CD133 (o), CD34 (p) and CD44 (q)) in indicated cells by QRT-PCR analysis. r. Slug expression recovers ALDH activity in indicated cells by flow cytometry.