Table 5. The association of haplotypes of the SNPs in ANRIL gene with the risk of MI.
| Haplotypea | Controls | Cases | OR (95% CI) | P |
|---|---|---|---|---|
| No. (%) | No. (%) | |||
| Total | n =646 | n = 286 | ||
| A T C G | 910.21 (70.5) | 380.85 (66.6) | 0.83 (0.67-1.02) | 0.080 |
| G C T C | 188.74 (14.6) | 87.00 (15.2) | 1.05 (0.79-1.38) | 0.749 |
| G T C C | 152.65 (11.8) | 82.85 (14.5) | 1.26 (0.95-1.68) | 0.113 |
| G T C G | 23.96 (1.9) | 15.15 (2.6) | 1.44 (0.75-2.76) | 0.273 |
| Non-drinkers | n =555 | n = 207 | ||
| A T C G | 789.61 (71.1) | 271.90 (65.7) | 0.77 (0.60-0.98) | 0.034b |
| G C T C | 154.74 (13.9) | 66.00 (15.9) | 1.17 (0.86-1.60) | 0.328 |
| G T C C | 132.33 (11.9) | 62.91 (15.2) | 1.32 (0.96-1.83) | 0.090 |
| G T C G | 20.91 (1.9) | 9.10 (2.2) | 1.17 (0.53-2.57) | 0.697 |
Abbreviations: SNP, single nucleotide polymorphism; MI, myocardial infarction, OR, odds ratio; CI, confidence interval.
a The allelic sequence in the haplotypes is in the following order: rs10965215, rs76521274, rs76184305, rs10738605.
b P values under 0.05 were indicated in bold font.