Table 2. Conventional US and SWS imagine features in predicting thyroid malignancy.

Parameter	Benign Nodules n = 216 (%)	Malignant Nodules n = 106 (%)	P value	Cut-off value	SEN (%)	SPE (%)	PPV (%)	NPV (%)	ACU (%)	AUC&
Solid Component		< 0.001		89.6	34.3	40.1	87.1	52.5	0.619 (0.564–0.673)
Yes	142 (65.7)	95 (89.6)
No	74 (34.3)	11 (10.4)
Hypoechogenicity			< 0.001		70.8	52.3	42.1	78.5	58.4	0.615 (0.560–0.669)
Yes	103 (47.7)	75 (70.7)
No	113 (52.3)	31 (29.3)
Taller-than-Wide Shape			< 0.001		43.4	81.0	52.9	74.5	68.6	0.622 (0.567–0.675)
Yes	41 (19.0)	46 (43.4)
No	175 (81.0)	60 (56.6)
Microcalcification			< 0.001		62.3	75.0	55.0	80.2	70.8	0.686 (0.633–0.737)
Yes	54 (25.0)	66 (62.3)
No	162 (75.0)	40 (37.7)
Poorly-defined Margin			< 0.001		82.1	69.4	56.9	88.8	73.6	0.758 (0.707–0.803)
Yes	66 (30.6)	87 (82.1)
No	150 (69.4)	19 (17.9)
Halo sign			0.092		17.0	74.5	24.7	64.7	55.6	0.542 (0.486–0.598)
Yes	55 (25.5)	18 (17.0)
No	161 (74.5)	88 (83.0)
Vascularity			0.448		34.9	69.4	35.9	68.5	58.1	0.522 (0.466–0.577)
I–II	150 (69.4)	69 (65.1)
III–IV	66 (30.6)	37 (34.9)
SWS imagine(kpa)
E-max	29.18 ± 18.62	61.27 ± 36.31	< 0.001	47.00	59.4	89.8	74.1	81.9	79.8	0.796 (0.748–0.839)
E-mean	15.85 ± 6.96	31.89 ± 19.11	< 0.001	23.00	60.4	91.2	77.1	82.4	81.1	0.807 (0.760–0.849)
SWS imagine(m/s)
E-max	2.98 ± 0.85	4.45 ± 1.49	< 0.001	3.52	69.8	81.5	64.9	84.6	77.6	0.813 (0.766–0.854) (0.748–0.839)
E-mean	2.19 ± 0.42	3.26 ± 2.71	< 0.001	2.46	67.9	83.3	66.7	84.1	78.3	0.800 (0.748–0.839)

Note–numbers in parentheses are percentages

Data are means ± standard deviations

SWS imagine = shear wave speed imagine; E-max = the max value of shear wave speed imagine; E-mean = the mean value of shear wave speed imagine ;

N/A = not apply

& Note–numbers in parentheses are 95% confidence interval (CI)

AUC = area under receiver operating characteristic curve; ACU = accuracy; NPV = negative predictive value; PPV = positive predictive value; SEN = sensitivity; SPE = specificity