Table 3. The diagnostic performances of SWS imagine in predicting thyroid malignancy with different sizes.
SWS indices | Cut-off value | SEN (%) | SPE (%) | PPV (%) | NPV (%) | ACU (%) | AUC& | P* | P# | P& | P^ | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Nodule size ≤ 10 mm (n = 123) | 0.528 | 0.083 | 0.031 | 0.003 | ||||||||
E-max | kpa | 24.4 | 76.9 | 76.2 | 60.0 | 87.7 | 76.4 | 0.776 (0.692,0.846) | ||||
m/s | 2.82 | 76.9 | 72.6 | 56.6 | 87.1 | 74.0 | 0.788 (0.705,0.857) | |||||
E-mean | kpa | 19.3 | 43.6 | 88.1 | 63.0 | 77.1 | 74.0 | 0.696 (0.607,0.776) | ||||
m/s | 2.61 | 41.0 | 89.3 | 64.0 | 76.5 | 74.0 | 0.672 (0.581,0.754) | |||||
11 ≤ Nodule size ≤ 20 mm (n = 132) | 0.668 | 0.334 | 0.583 | 0.435 | ||||||||
E-max | kpa | 46.9 | 80.0 | 91.5 | 85.1 | 88.2 | 87.1 | 0.894 (0.829,0.941) | ||||
m/s | 3.92 | 78.0 | 92.7 | 86.7 | 87.4 | 87.1 | 0.895 (0.830,0.942) | |||||
E-mean | kpa | 22.5 | 74.0 | 91.5 | 84.1 | 85.2 | 84.8 | 0.883 (0.815,0.932) | ||||
m/s | 2.45 | 82.0 | 84.1 | 76.0 | 88.5 | 83.3 | 0.876 (0.808,0.927) | |||||
Nodule size >20 mm (n = 67) | 0.193 | 0.685 | 0.251 | 0.911 | ||||||||
E-max | kpa | 52.4 | 88.2 | 82.0 | 62.5 | 95.3 | 83.6 | 0.810 (0.696,0.896) | ||||
m/s | 4.13 | 94.1 | 84.0 | 66.7 | 97.7 | 86.6 | 0.883 (0.781,0.949) | |||||
E-mean | kpa | 27.8 | 70.6 | 92.0 | 75.0 | 90.2 | 86.6 | 0.886 (0.785,0.951) | ||||
m/s | 2.67 | 76.5 | 88.0 | 68.4 | 91.7 | 85.1 | 0.877 (0.774,0.945) |
AUC=area under receiver curve; ACU,=accuracy; NPV=negative predictive value; PPV=positive predictive value; SEN=sensitivity; SPE= specificity; SWS=shear wave speed; E-max = the max value of shear wave speed imagine; E-mean = the mean value of shear wave speed imagine ;
& Note–numbers in parentheses are 95% confidence intervals (CI)
P* AUC in comparison with that of E-max between elasticity and speed
P# AUC in comparison with that of E-mean between elasticity and speed
P& AUC in comparison with that of E-max elasticity and E-mean elasticity
P^ AUC in comparison with that of E-max speed and E-mean speed