Figure 2. Imetelstat increases cell apoptosis of Kyse410 and Kyse520 cell.

Kyse410 and Kyse520 cells were incubated and treated with 5 μM sense or imetelstat for 72 h and at the same time exposed to 10 μM TMZ. Results of early and late apoptosis were added together to calculate the total amount of apoptosis. Values represent the mean±SD and are representative of three independent experiments. *p < 0.05, statistical significance was established by t test.