Table 2. Univariate and multivariate analyses of overall survival in NSCLC patients.
Variable | Univariate | Multivariate | ||
---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Gender | 0.537 | |||
Female | 1.000 | |||
Male | 1.120 (0.781-1.605) | |||
Age (y) | 0.174 | |||
≤60 | 1.000 | |||
>60 | 1.297 (0.892-1.885) | |||
Histologic type | 0.084 | |||
AC | 1.000 | |||
SC | 0.669 (0.424-1.055) | |||
Differentiation | 0.486 | |||
Well | 1.000 | |||
Moderate | 1.256 (0.846-1.863) | |||
Poor | 1.237 (0.736-2.078) | |||
pT category | <0.001 | 0.038 | ||
T1-T2 | 1.000 | 1.000 | ||
T3-T4 | 2.198 (1.411-3.424) | 1.624 (1.028-2.563) | ||
pN category | <0.001 | 0.006 | ||
Negative | 1.000 | 1.000 | ||
Positive | 2.253 (1.556-3.240) | 1.726 (1.171-2.543) | ||
Distant metastasis | <0.001 | <0.001 | ||
Negative | 1.000 | 1.000 | ||
Positive | 6.583 (3.158-13.725) | 3.920 (1.829-8.400) | ||
TNM stage | <0.001 | |||
I-II | 1.000 | |||
III-IV | 3.847 (2.503-5.913) | |||
FSIP status | <0.001 | 0.001 | ||
Negative | 1.000 | 1.000 | ||
Positive | 2.176 (1.489-3.180) | 1.876 (1.274-2.764) | ||
Ki67 status | 0.006 | 0.019 | ||
Negative | 1.000 | 1.000 | ||
Positive | 1.769 (1.179-2.654) | 1.629 (1.082-2.453) |
Abbreviation, AC: adenocarcinoma; FSIP1: fibrous sheath interacting protein 1; SC: squamous carcinoma.