Table 2. Main characteristics of included studies.
| Author | Country | Sample (M/T) | Methylation in NSCLC(%) Avg. 26.78% |
WIF1 Methylation (M/T) |
WIF1 Methylation (M/T) |
Wif1 Expression in NSCLC | Methylation site | Methods | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| NSCLC | Normal | Smoking | Non-smoking | Male | Female | ||||||
| Suzuki | Japan | 42/177 | 4/80 | 23.7 | 48/162 | 14/67 | 46/160 | 16/69 | N/A | Promoter | MSP |
| Yoshino | Japan | 7/44 | 2/32 | 15.9 | 5/22 | 2/10 | 4/22 | 3/22 | N/A | Promoter | MSP |
| Ren | China | N/A | N/A | N/A | N/A | N/A | Promoter | MSP | |||
| Mazieres | USA | 15/18 | 0/18 | 83.3 | N/A | N/A | 3/18 | Promoter | MSP | ||
Abbreviations: NSCLC: Non-small cell lung cancer, M: Methylation, T: Total, N/A: Not available, MSP: Methylation-specific PCR