Figure 7. Cats overexpression reduces the number of colony formation and total cell number of primary bone marrow progenitor cells.

A. Transduced cells were cultured in myeloid-conditioned methylcellulose medium for 8 days after which colonies were counted. The bars represent the number of GM (granulocytes and monocytes), BFU-E (erythrocytes) and GEMM (progenitors) colonies and B. the total number of cells. C. Cells were replated in the same concentration and further cultured for 10 days, allowing secondary colony formation. The bars indicate the number of secondary GM colonies. Results are shown as mean ± SD of three independent experiments. *p<0.05; **p<0.01, Student's t test.