Skip to main content
. 2016 Oct 19;7(51):84893–84906. doi: 10.18632/oncotarget.12753

Figure 1. Elevated ZNF217 expression aggravates iron-related tumor cell growth.

Figure 1

A. The mRNA and protein level of ZNF217 in four different PCa cell lines (i.e. PC3, DU145, LNCaP and C4-2) and prostatic epithelial cell line RWPE-1 by qPCR and Western blot analysis, respectively. B, F. The mRNA and protein level of ZNF217 were assessed upon ZNF217 knockdown in PC3 cells or overexpression in LNCaP cells. C, G. The cell growth were examined upon ZNF217 knockdown in PC3 cells or overexpression in LNCaP cells. D, H. The cell cycle was detected upon ZNF217 knockdown in PC3 cells or overexpression in LNCaP cells. E, J. The final tumor weight of tumors derived from ZNF217 knockdown PC3 cells or ZNF217 transfected LNCaP cells. F, K. The tissue iron levels in tumor samples upon ZNF217 knockdown in PC3 cells or overexpression in LNCaP cells. Data depict the mean ± SD and representative of six independent experiments. Asterisk (*) indicates P < 0.05