Table 2. Univariate cox regression analysisof prognostic factors for overall survival rates of astrocytoma patients.
Variety | Classification | Death cases/Total cases | Median survival time | 1 year/3 year overall survival | p | HR(95%CI) |
---|---|---|---|---|---|---|
Total | / | 147/160 | 11 | 28.8%/6.6% | / | / |
Sex | Male | 80/88 | 11 | 26.1%/6.8% | 0.769 | 1 |
Female | 67/72 | 11 | 31.9%/6.3% | 1.05(0.76-1.44) | ||
Age | < 40years | 58/66 | 11 | 31.8%/8.6% | 0.186 | 1 |
≥40years | 89/94 | 10 | 26.6%/- | 1.23(0.88-1.71) | ||
WHO classification extent of surgical resection | I-II grade | 86/96 | 11 | 28.1%/ | 0.612 | 1 |
III grade | 61/64 | 11 | 29.7%/3.9% | 1.08(0.78-1.50) | ||
Not all resection | 98/111 | 9 | 16.3%/- | 0.003 | 1 | |
Total resection | 49/49 | 11 | 34.2%/9.6% | 0.61(0.43-0.88) | ||
Radiotherapy | No | 11/14 | 12 | 46.2%/- | 0.334 | 1 |
Conformal radiotherapy | 38/41 | 9 | 14.6%/8.8% | 1.48(0.75-2.91) | ||
Gamma knife | 99/106 | 11 | 32.1%/- | 1.18(0.63-2.21) | ||
Chemotherapy | No | 96/102 | 9 | 23.5%/- | 0.029 | 1 |
Yes | 51/58 | 12 | 37.9%/11.4% | 0.71(0.49-0.99) |
p<0.05 indicates statistical significance; HR: hazard ratios; CI: confidence interval.