Table 4. The polymorphisms of genotype model in the cases and controls and the associations with T2D risk (adjust by age and gender).
| SNP | Genotype | Control | Case | OR (95% CI) | p-value |
|---|---|---|---|---|---|
| rs2811893 | T/T | 159 (41.1%) | 130 (40.9%) | 1 | 0.470 |
| C/T | 169 (43.7%) | 148 (46.5%) | 1.08 (0.78-1.48) | ||
| C/C | 59 (15.2%) | 40 (12.6%) | 0.81 (0.51-1.29) | ||
| rs13064954 | G/G | 305 (78.8%) | 257 (80.6%) | 1 | 0.420 |
| G/A | 80 (20.7%) | 58 (18.2%) | 0.87 (0.60-1.27) | ||
| A/A | 2 (0.5%) | 4 (1.2%) | 2.46 (0.44-13.64) | ||
| rs17376456 | A/A | 329 (85%) | 280 (87.8%) | 1 | 0.310 |
| G/A | 57 (14.7%) | 39 (12.2%) | 0.79 (0.51-1.23) | ||
| G/G | 1 (0.3%) | 0 (0%) | 0.00 (0.00-NA) | ||
| rs7772697 | T/T | 270 (70%) | 223 (69.9%) | 1 | 0.360 |
| C/T | 109 (28.2%) | 85 (26.6%) | 0.92 (0.66-1.29) | ||
| T/T | 7 (1.8%) | 11 (3.5%) | 1.88 (0.71-4.97) | ||
| rs3918227 | C/C | 339 (87.6%) | 270 (84.6%) | 1 | 0.046 |
| C/A | 45 (11.6%) | 49 (15.4%) | 1.41 (0.91-2.20) | ||
| A/A | 3 (0.8%) | 0 (0%) | 0.00 (0.00-NA) | ||
| rs4838605 | T/T | 316 (81.7%) | 243 (76.2%) | 1 | 0.003* |
| C/T | 66 (17.1%) | 76 (23.8%) | 1.54 (1.06-2.24) | ||
| C/C | 5 (1.3%) | 0 (0%) | 0.00 (0.00-NA) | ||
| rs6214 | C/C | 108 (27.9%) | 105 (32.9%) | 1 | 0.310 |
| C/T | 191 (49.4%) | 142 (44.5%) | 0.76 (0.54-1.08) | ||
| T/T | 88 (22.7%) | 72 (22.6%) | 0.84 (0.56-1.28) |
CI = confidence interval; OR = odds ratio; SNP = single nucleotide polymorphism;
*p ≤ 0.05 indicates statistical significance.