Table 1. Levels of cytokines (pg/mg) and ROS (/%) in SAMR1, SAMP8 and following SS31 treatment (mean ± SD).
Groups | TNF-α* | IL-1β** | IL-2 | IL-6* | IL-10 | ROS** |
---|---|---|---|---|---|---|
SAMR1 | 24.75±5.44 | 38.75±9.22 | 179.00±56.15 | 8.25±3.30 | 32.75±12.04 | 100.00±39.23 |
SAMP8 | 40.50±12.40& | 57.50±3.42& | 266.75±14.01 | 13.75±2.50& | 37.25±5.68 | 294.83±92.91& |
SS31 | 28.50±8.39 | 40.75±5.06# | 233.74±74.91 | 10.10±3.92 | 37.50±12.92 | 208.78±56.64# |
Overall analysis: * P < 0.05; ** P < 0.01
Posthoc analysis: & P < 0.05: SAMP8 vs. SAMR1 mice; #P < 0.05: SS31 vs. SAMP8 mice.