Table 2. Potential miRNAs as treatment targets for AML.
miRNA | target genes or pathways | References |
miR-141 | PI3K/Akt/mTOR | [113] |
miR-125a | ErbB pathway | [10] |
miR-125b | Mcl-1 | [11, 12] |
miR-22-3p, let-7e-5p | PLK1 | [114] |
miR-34a | PD-L1 | [80] |
miR-638 | CDK2 | [34] |
miR-181a, b and c | PRKCD, CTDSPL and CAMKK1 | [6, 36, 96, 97] |
miR-191-5p, miR-142-3p | PPP2R2A | [19, 115] |
miR-181b | MDR | [36] |
miR-21, miR-196b | HOX | [98] |
miR-29a/b/c | Dnmts | [19, 22] |