Table 1. Pathways regulated by KLK6 proteolysis.
| Pathway | Protein | TAILS | Position |
|---|---|---|---|
| WNT/BMP | Dickkopf-related protein 1; DKK1 | 6.741,7.6543.041, 4.533.0412.221 | R235 R190 T180 G91 |
| Na(+)/H(+) exchange regulatory cofactor NHE-RF1; SLC9A3R1 | 6.741,3.2141.25 | R179 R219 |
|
| IGFs | Insulin-like growth factor-binding protein 2; IBP2 | 5.7415.741, 5.7024.42 | K215 F39 E192 |
| Insulin-like growth factor-binding protein 4; IBP4 | 5.157, 4.4603.741 | R36 R48 |
|
| Insulin-like growth factor 2; IGF2 | 9.9664.1561.315, 1.978 | E35 G64 R63 |
|
| TGFs | Latent-transforming growth factor beta-binding protein 4; LTBP4 | 9.9669.9662.934 | R622 R472R 335 |
| Latent-transforming growth factor beta-binding protein 3; LTBP3 | 9.9663.157 | R377 F724 |