Table 2. Immunophenotype and cytogenetic features of SaMMi MM cell line.
Cell type | CD138 | CD38 | CD117 | CD19 | CD56 | CD45 | Mono κ | Mono λ |
---|---|---|---|---|---|---|---|---|
SaMMi | + | – | – | – | + | + | - | + |
MM | + | +/– | +/– | – | + | + | +/– | +/– |
SaMMi was compared with common MM cell lines (MM). Mono κ and Mono λ refer to clonal restriction for κ and λ light chain, respectively. The karyotype of SaMMi is the following:
45,X,-X,idic(1)(p11),der(1)t(1;3)(q25;q21),del(4)(q25),t(4;12)(q26;q13),
der(14)t(11;14)(q13;q32)t(8;14)(q23;q32),der(9)del(9)(p21)t(1;18;9)(q12;p11;q34)[25].ish idic(1)
(p11)(CDKN2C-,CKS1B++),der(1)t(1;3)(CDK2C+,CKS1B+)del(17)(p13.1p13.1)(TP53-,
17p11.1-q11.1+),der(18)t(1;18;9)(CKS1B+)[4].