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A and C. Realtime PCR was used to detect the expression of IL-6 in N-FLSs and RA-FLSs; B and D. ELISA was employed to detect the expression of IL-6 in the conditioned mediums obtained from RA-FLSs and N-FLSs Data represent three independent experiments with SD. Statistically significant differences are shown (*P < 0.05; **P<0.01, NS means no significant).
