Table 2. Association of COP-MPV with the clinicolaboratory characteristics of patients with NSCLC.
| Variables | COP-MPV=0(n=119) | COP-MPV=1(n=295) | COP-MPV=2(n=132) | P value |
|---|---|---|---|---|
| Age (year) | 59.8±8.4 | 60.9±9.7 | 59.9±9.2 | 0.423 |
| Hb (gL-1) | 139.2±14.5 | 141.1±14.0 | 134.7±19.7 | <0.001 |
| LDH (UL-1) | 178.4±36.8 | 185.7±60.9 | 180.6±45.1 | 0.961 |
| ALP (UL-1) | 74.2±26.6 | 72.5±19.8 | 81.8±33.6 | 0.019 |
| WBC count(×103/μL) | 6.4±1.8 | 6.8±1.5 | 7.4±1.8 | <0.001 |
| PLT (×109L-1) | 231.2±25.7 | 261.7±46.7 | 343.7±65.2 | <0.001 |
| MPV (fL) | 12.0±1.3 | 10.8±0.3 | 10.6±0.4 | <0.001 |
| RDW (%) | 13.2±0.9 | 13.0±0.8 | 13.4±1.6 | 0.019 |
| Albumin (gL-1) | 43.4±3.9 | 43.1±4.1 | 41.8±4.5 | 0.004 |
| D-dimer (mgL-1) | 0.18±0.11 | 0.21±0.28 | 0.20±0.12 | 0.049 |
| Fibrinogen (gL-1) | 3.5±0.9 | 3.5±0.9 | 4.2±1.0 | <0.001 |
| Maximum tumor diameter (cm) | 3.9±1.9 | 4.1±1.9 | 5.4±2.5 | <0.001 |
| Survival period (m) | 57.0±19.6 | 42.6±25.4 | 37.9±24.5 | <0.001 |
Abbreviations: COP-MPV, combination of preoperative platelet count and mean platelet volume; NSCLC, non-small cell lung cancer; Hb, hemoglobin; LDH, lactate dehydrogenase; ALP, alkaline phosphatase; WBC, white blood cell; PLT, platelet count; MPV, mean platelet volume; RDW, red blood cell distribution width.
P less than .05 is statistically significant.