Figure 4. Propofol decreases and etomidate increases AKT activation and epithelial-mesenchymal transition (EMT).
(A) Western blotting analysis of EMT markers and phosphorylated AKT in SW480 and HCT116 cells treated with 100 μg/ml of dexmedetomidine in combined with 2 or 4 μg/ml of propofol for 24 h. (B) Western blotting analysis of EMT markers and phosphorylated AKT in SW480 and HCT116 cells treated with 100 μg/ml of dexmedetomidine in combined with 2 or 4 μg/ml of etomidate for 24 h. Representative figures were shown. The results were reproduced in 3 independent experiments.