In the article titled “Predictive Value of Plasma MicroRNA-216a/b in the Diagnosis of Esophageal Squamous Cell Carcinoma” [1], there was an error in Table 1. The heading incorrectly referred to miRNA-718 expression instead of miRNA-216a/b. miRNA-718 expression is the subject of a related article, Sun L, Dong S, Dong C, Sun K, Meng W, Lv P, Yin H, Ming L, He F: “Predictive value of plasma miRNA-718 for esophageal squamous cell carcinoma”. Cancer Biomark. 2016;16(2):265-73. doi: 10.3233/CBM-150564. The table should be corrected as follows.
Table 1.
Clinicopathological characteristics of patients with ESCC.
Characteristics | n (%) | Plasma miRNA relative expression level (mean ± SD) | |||
---|---|---|---|---|---|
miR-216a | P value | miR-216b | P value | ||
Age (year) | 0.1082 | 0.2125 | |||
≤63 | 46 (38.3) | 0.058 ± 0.048 | 0.079 ± 0.086 | ||
>63 | 74 (61.7) | 0.074 ± 0.054 | 0.099 ± 0.087 | ||
Gender | 0.5388 | 0.5912 | |||
Male | 79 (65.8) | 0.070 ± 0.055 | 0.094 ± 0.087 | ||
Female | 41 (34.2) | 0.064 ± 0.048 | 0.085 ± 0.089 | ||
Smoking | 0.1342 | 0.6168 | |||
Never | 52 (43.3) | 0.060 ± 0.047 | 0.087 ± 0.079 | ||
Ever | 68 (56.7) | 0.074 ± 0.056 | 0.095 ± 0.093 | ||
Alcohol use | 0.2378 | 0.5386 | |||
Never | 40 (33.3) | 0.060 ± 0.054 | 0.098 ± 0.087 | ||
Ever | 80 (66.7) | 0.072 ± 0.051 | 0.088 ± 0.087 | ||
Tumor location | 0.3136 | 0.1810 | |||
Upper esophagus | 11 (9.2) | 0.065 ± 0.061 | 0.106 ± 0.092 | ||
Middle esophagus | 70 (58.3) | 0.074 ± 0.056 | 0.100 ± 0.096 | ||
Low esophagus | 39 (32.5) | 0.058 ± 0.041 | 0.072 ± 0.066 | ||
Histologic grade | 0.8959 | 0.8308 | |||
Well differentiated | 33 (27.5) | 0.070 ± 0.059 | 0.109 ± 0.112 | ||
Moderate differentiated | 70 (58.3) | 0.068 ± 0.052 | 0.089 ± 0.082 | ||
Poor differentiated | 17 (14.2) | 0.063 ± 0.040 | 0.068 ± 0.030 | ||
T stage | 0.3206 | 0.6600 | |||
Tis-T1 | 36 (30.0) | 0.075 ± 0.061 | 0.115 ± 0.114 | ||
T2 | 28 (23.3) | 0.086 ± 0.065 | 0.100 ± 0.090 | ||
T3 | 41 (34.2) | 0.056 ± 0.037 | 0.074 ± 0.065 | ||
T4 | 15 (12.5) | 0.050 ± 0.019 | 0.067 ± 0.031 | ||
Lymph node metastasis | 0.0845 | 0.0168 | |||
Negative | 42 (35.0) | 0.088 ± 0.068 | 0.134 ± 0.117 | ||
Positive | 78 (65.0) | 0.057 ± 0.038 | 0.068 ± 0.054 | ||
TNM stage | 0.0054 | 0.0359 | |||
0-I | 29 (24.2) | 0.088 ± 0.062 | 0.134 ± 0.119 | ||
II | 28 (23.3) | 0.086 ± 0.065 | 0.101 ± 0.090 | ||
III | 40 (33.3) | 0.058 ± 0.035 | 0.072 ± 0.067 | ||
IV | 23 (19.2) | 0.039 ± 0.022 | 0.060 ± 0.029 |
References
- 1.Dong S., Yin H., Dong C., et al. Predictive value of plasma MicroRNA-216a/b in the diagnosis of esophageal squamous cell carcinoma. Disease Markers. 2016;2016:8. doi: 10.1155/2016/1857067.1857067 [DOI] [PMC free article] [PubMed] [Google Scholar]