Table 1. Clinical characteristics and body composition of study subjects.
Data are presented as mean ± SD for continuous variables and n for categorical variables
| Non-T2DM (n=13) | T2DM (n=8) | p | |
|---|---|---|---|
| Age (years) | 48.2 ± 10.9 | 50.3 ± 12.0 | 0.9 |
| Premenopausal women/Postmenopausal women/Men (n) |
8/3/2 | 3/4/1 | 0.6 |
| Fracture History (n) | 3 | 3 | 0.6 |
| Weight (kg) | 121 ± 18 | 109 ± 10 | 0.1 |
| BMI (kg/m2) | 45.4 ± 5.7 | 41.5 ± 4.0 | 0.1 |
| Visceral Adipose Tissue (cm2) | 220 ± 33 | 185 ± 101 | 0.5 |
| Subcutaneous Adipose Tissue (cm2) | 483 ± 119 | 481 ± 114 | 0.9 |
| Race/Ethnicity | 0.01 | ||
| White non-hispanic | 11 | 3 | |
| White hispanic | 2 | - | |
| African American non-hispanic | - | 4 | |
| African American hispanic | - | 1 | |
| Serum fasting glucose (mg/dl) | 93 ± 8 | 101 ± 23 | 0.3 |
| Serum calcium (mg/dl) | 9.6 ± 0.5 | 9.5 ± 0.5 | 1.0 |
| Serum 25-hydoxyvitamin D (ng/ml) | 25 ± 5 | 33 ± 14 | 0.1 |
| Serum PTH (pg/ml) | 49 ± 17 | 69 ± 35 | 0.2 |
| HbA1c (%) | 5.3 ± 0.3 | 6.3 ± 0.4 | <0.0001 |
| Insulin (μIU/ml) | 13.4 ± 9.8 | 25.3 ± 15.9 | 0.02 |
| HOMA IR | 3.2 ± 2.7 | 6.0 ± 3.6 | 0.02 |
| Triglycerides (mg/dl) | 132 ± 76 | 97 ± 46 | 0.3 |
| Total Cholesterol (mg/dl) | 194 ± 25 | 160 ± 28 | 0.02 |
| LDL (mg/dl) | 117 ± 23 | 90 ± 24 | 0.02 |
| HDL (mg/dl) | 51 ± 8 | 51 ± 14 | 1.0 |
T2DM: type 2 diabetes mellitus; PTH: parathyroid hormone, HbA1c: hemoglobin A1c, HOMA IR: homeostasis model assessment of insulin resistance, LDL: low-density lipoprotein, HDH: high-density lipoprotein. P-values < 0.05 are bolded.