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. 2017 Jan 27;8(10):16473–16487. doi: 10.18632/oncotarget.14869

Figure 1. Mouse/Human array data comparison identifies MTSS1 as an inflammation linked gene that predicts poor prognosis in human PDAC.

Figure 1

(A) Masson's trichrome staining for reactive stroma presence in samples from wild type mice, KrasG12D/+;Ptenlox/+ mice, and KrasG12D/+;Ptenlox/+;Cox-2 COE mice. (B) Quantification of staining intensity of Masson's trichrome staining of tissue from wild type mice, KrasG12D/+;Ptenlox/+ mice, and KrasG12D/+;Ptenlox/+;Cox-2 COE mice. (C) Schematic detailing strategy for comparing mouse and human array data in order to obtain a list of genes that are differentially expressed in KrasG12D/+;Ptenlox/+;Cox-2 COE mice that also predict survival in human PDAC patients. *p-value < 0.05, ***p-value < 0.0001.