Table 1. Multivariate cox regression analysis for AHNAK mutated samples and other prognostic markers using TCGA cohort.
| Factor | No. of patients | HR | B (coefficient) | P value |
|---|---|---|---|---|
| I. Univariate analysis TCGA dataset | ||||
| Age | 254 | 1.037 | 0.036 | <0.0001 |
| G-CIMP | 253 | 0.220 | -1.512 | 0.003 |
| MGMT | 192 | 0.552 | -0.594 | 0.002 |
| IDH | 254 | 0.240 | -1.426 | 0.005 |
| AHNAK | 254 | 2.646 | 0.973 | 0.020 |
| II. Multivariate analysis with TCGA dataset | ||||
| Age | 254 | 1.037 | 0.037 | <0.0001 |
| AHNAK | 2.667 | 0.981 | 0.020 | |
| G-CIMP | 253 | 0.224 | -1.496 | 0.003 |
| AHNAK | 2.467 | 0.903 | 0.032 | |
| MGMT | 192 | 0.550 | -0.598 | 0.002 |
| AHNAK | 2.605 | 0.957 | 0.039 | |
| IDH | 254 | 0.244 | -1.409 | 0.005 |
| AHNAK | 2.502 | 0.917 | 0.029 | |
| III. Multivariate analysis of all the markers in TCGA dataset | ||||
| Age | 192 | 1.041 | 0.041 | <0.0001 |
| G-CIMP | 0.000 | -10.182 | 0.954 | |
| MGMT | 0.713 | -0.339 | 0.081 | |
| IDH | 10004.361 | 9.211 | 0.959 | |
| AHNAK | 2.562 | 0.941 | 0.043 | |