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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 2017 Mar 13;114(12):E2542. doi: 10.1073/pnas.1701795114

Correction for Jeon et al., A set of NF-κB–regulated microRNAs induces acquired TRAIL resistance in Lung cancer

PMCID: PMC5373374  PMID: 28289189

CELL BIOLOGY Correction for “A set of NF-κB–regulated microRNAs induces acquired TRAIL resistance in Lung cancer,” by Young-Jun Jeon, Justin Middleton, Taewan Kim, Alessandro Laganà, Claudia Piovan, Paola Secchiero, Gerard J. Nuovo, Ri Cui, Pooja Joshi, Giulia Romano, Gianpiero Di Leva, Bum-Kyu Lee, Hui-Lung Sun, Yonghwan Kim, Paolo Fadda, Hansjuerg Alder, Michela Garofalo, and Carlo M. Croce, which appeared in issue 26, June 30, 2015, of Proc Natl Acad Sci USA (112:E3355–E3364; first published June 15, 2015; 10.1073/pnas.1504630112).

The editors wish to note that, after this article was published, a reader noticed that some fragments of text and some sentences in the introduction, results, and discussion overlap with text from other articles and were reproduced without quotation marks. The editors wish to include the relevant text and references below. No concerns have been raised about the originality of the research or about the results and conclusions.

In the introduction, some text from sentences 1, 6–8, 12, and 13 overlaps substantially with text from the following work, which was not originally cited:

Habelhah H (2010) RIP1 cleavage by caspase-8 is essential for TRAIL-induced NF-κB activation (University of Iowa, Iowa City, IA). Available at grantome.com/grant/NIH/R01-CA138475-01A1.

In the introduction, sentences 2 and 3 overlap substantially with text from the following work, which was not originally cited:

Bellail AC, Olson JJ, Yang X, Chen ZJ, Hao C (2012) A20 ubiquitin ligase–mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma. Cancer Discov 2(2):140–155.

Sentence 4 of the introduction overlaps substantially with text from the work below, which was not originally cited: “The other two receptors, DcR1 and DcR2, are ‘decoy receptors’ and lack the ability to initiate the apoptotic cascade.”

Garofalo M, et al. (2008) MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer. Oncogene 27(27):3845–3855.

Sentence 16 of the introduction overlaps substantially with text from the work below, which was not originally cited: “Lung cancer is the leading cause of cancer-related mortality, not only in the United States but also around the world.”

Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA (2008) Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 83(5):584–594.

Sentence 8 of paragraph 3 in the discussion overlaps substantially with text from the work below, which was not originally cited: “TRAFs were initially discovered as adaptor proteins that couple the TNF receptor family to signaling pathways.”

Bradley JR, Pober JS (2001) Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 20(44):6482–6491.

In the discussion, paragraph 3, sentence 21 overlaps substantially with text from ref. 49 and is now shown with quotation marks below:

“Genetic inhibition of the NF-ĸB pathway affects both the initiation and the maintenance of lung cancer, identifying this pathway as a promising therapeutic target [49]” (49).

49. Xue W, et al. (2011) Response and resistance to NF-ĸB inhibitors in mouse models of lung adenocarcinoma. Cancer Discov 1(3):236–247.


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